IJREH | Evaluation of effects of Curcuma amada extracts on 6-OHDA-induced behavioral alterations

Indexing and Abstracting

Evaluation of effects of Curcuma amada extracts on 6-OHDA-induced behavioral alterations

Swayam Sampurna Mohanty , Shaktikumar Chandrashekhar Shivhare

International Journal of Rural Development, Environment and Health Research(IJREH), Vol-8,Issue-1, January - March 2024, Pages 1-5,

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Article Info: Received: 15 Nov 2023; Received in revised form: 17 Dec 2023; Accepted: 25 Dec 2023; Available online: 03 Jan 2024

Abstract:

In the current work, 6-OHDA injection intrastriatally severely reduced motor function in rats. Similar to previous research showing that motor deficits in Parkinsonian rats can be mitigated by antioxidant supplementation (Zafar et al., 2003a), we found that Curcuma amada significantly and dose-dependently restored locomotor deficits in 6-OHDA-lesioned rats.

Keywords:

Curcuma amada, 6-OHDA, Parkinson, Ethanolic extract, Methanolic extract, Aqueous extract.

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