IJREH | Enhancement of Aqueous Solubility of Piroxicam Using Solvent Deposition System

Indexing and Abstracting

Enhancement of Aqueous Solubility of Piroxicam Using Solvent Deposition System

Mr. Ubale Amol Tanaji , Dr. Mayank Mandhanya , Dr. Vivek Subhash Tarate

International Journal of Rural Development, Environment and Health Research(IJREH), Vol-8,Issue-1, January - March 2024, Pages 15-16,

Download | Downloads : 2 | Total View : 78

Abstract:

Piroxicam is a non-steroidal anti-inflammatory drug that is characterized by low solubility-high permeability. The present study was designed to improve the dissolution rate of piroxicam at the physiological pH's through its increased solubility by using solvent deposition system.

Keywords:

NSAID, Piroxicam, SDS, solubility enhancement, Lactose

References:

[1] Amidon GL, Lennernäs H, Shah VP, Crison JR. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharmaceutical research. 1995 Mar;12:413-20.
[2] Cavallari C, Abertini B, González-Rodrı́guez ML, Rodriguez L. Improved dissolution behaviour of steam-granulated piroxicam. European journal of pharmaceutics and biopharmaceutics. 2002 Jul 1;54(1):65-73.
[3] E. Kalumanga, V., & J. Mahimbo, F. (2023). The Influence of Maize Cluster Development Interventions on the Performance of Actors in Morogoro Region, Tanzania. In International Journal of Environment, Agriculture and Biotechnology (Vol. 8, Issue 5, pp. 058–066). AI Publications. https://doi.org/10.22161/ijeab.85.10
[4] Karataş A, Yüksel N, Baykara T. Improved solubility and dissolution rate of piroxicam using gelucire 44/14 and labrasol. Il Farmaco. 2005 Sep 1;60(9):777-82.
[5] Miah, Md. G. R., Karim, A. J. M. S., Islam, Md. M., Islam, Md. D., & Kamal, M. Z. U. (2023). Effects of water stress and nutrient management on the performance of tomato. In International Journal of Environment, Agriculture and Biotechnology (Vol. 8, Issue 6, pp. 001–010). AI Publications. https://doi.org/10.22161/ijeab.86.1