• editor.aipublications@gmail.com
  • Track Your Paper
  • Contact Us
  • ISSN: 2456-8015

International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

The Association between Vitamin D3 and Ca levels with Diabetes Type one

Farah Thamer Hasan , Mustafa Mamon Ahmed , Noaman Abdulateef Abdulrazzaq


International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-6,Issue-6, November - December 2022, Pages 11-15 ,

Download | Downloads : 7 | Total View : 127

Article Info: 10.22161/ijmpd.6.6.3

Share

50 patients and 30 healthy controls in different gender are roughly selected in wide range of age between (18-80 years), taken from different private laboratories in Baghdad through the period (2021-2022). They were separated into two groups (male 39– female 11(patients)) (male 17- female 13) control and applied a vitamin D test and Ca level. This study is designed to investigate the possible association between Ca and Vit D3 levels and diabetes type one patient. A highly significant difference between the patient and healthy control in low Ca levels (p-value 0.0084 **) A highly significant difference between the patient and healthy control in normal Ca levels (p- value 0.0097 **) while no significant difference when the Ca level is high (p-value 0.894 NS). No significant difference between the patient and healthy control in Vit D3 deficiency group (p-value 0.083 NS) while there is a significant difference between the patient and healthy control in Vit D3 insufficient group (p- value 0.0392 *) while there is no significant difference in Suboptimal vit D3 level group (p-value 00.602 NS). Also there is no significant difference in optimal vit D3 level group (p-value 0.907 NS). The conclusion of this study suggests that Men may be more likely than women to develop type 1 diabetes within the area from which the samples were collected depending on the results. Smoking may also be an influential factor, regardless of gender. But also non-smoking people have the condition. Blood pressure was not a significant factor in this study. People with diabetes tend to have lower levels of calcium in their bodies than normal people. They also have insufficient levels of vitamin D compared to normal people.

Diabetes, type 1 diabetes, Vit D3, Calcium

[1] Jaffe, L. F. (1983). Sources of calcium in egg activation: a review and hypothesis. Developmental biology, 99(2), 265-276.
[2] Brownlee, M., VLASSARA, H., & Cerami, A. (1984). Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Annals of internal medicine, 101(4), 527-537.
[3] Fujita, T. (2000). Calcium paradox: consequences of calcium deficiency manifested by a wide variety of diseases. Journal of Bone and Mineral Metabolism, 18(4), 234-236
[4] Slawson, D. L., McClanahan, B. S., Clemens, L. H., Ward, K. D., Klesges, R. C., Vukadinovich, C. M., & Cantler, E. D. (2001). Food sources of calcium in a sample of African-American and Euro-American collegiate athletes. International journal of sport nutrition and exercise metabolism, 11(2), 199-208.
[5] Mellitus, D. (2005). Diagnosis and classification of diabetes mellitus. Diabetes care, 28(S37), S5-S10.
[6] Pittas, A. G., Lau, J., Hu, F. B., & Dawson-Hughes, B. (2007). The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. The Journal of Clinical Endocrinology & Metabolism, 92(6), 2017-2029.
[7] Zhu, J., Xun, P., Bae, J. C., Kim, J. H., Kim, D. J., Yang, K., & He, K. (2019). Circulating calcium levels and the risk of type 2 diabetes: a systematic review and meta-analysis. British Journal of Nutrition, 122(4), 376-387.
[8] Al-Yassin, D. A. M. H., Hussein, A. M., Ali, T., & Dohan, C. E. (2009). Calcium and diabetes mellitus type Two a prospective study done on people with type 2 diabetes in Diwaniya teaching hospital. Kufa Med. J, 12(1), 468-475.
[9] Mathieu, C., Gysemans, C., Giulietti, A., & Bouillon, R. (2005). Vitamin D and diabetes. Diabetologia, 48(7), 1247-1257.
[10] Pittas, A. G., & Dawson-Hughes, B. (2010). Vitamin D and diabetes. The Journal of steroid biochemistry and molecular biology, 121(1-2), 425-429.