• editor.aipublications@gmail.com
  • Track Your Paper
  • Contact Us
  • ISSN: 2456-8015

International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

Study of Spectrum of Adrenal Changes Autopsied at J.L.N. Hospital Ajmer

Dr. Manjeet Singh Kaviya , Dr. R.K Mathur , Dr. Ashutosh Srivastava , Dr. Rafeek Khan

International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-6,Issue-1, January - February 2022, Pages 1-8 , 10.22161/ijmpd.6.1.1

Download | Downloads : | Total View : 198

Article Info: Received: 03 Jan 2022; Received in revised form: 27 Jan 2022; Accepted: 6 Feb 2022; Available online: 13 Feb 2022


Background- Adrenal glands are the least studied organ. Aim and Objectives- 1. To analyse gross and microscopic morphology of adrenals in posmortem cases and their correlation if any with the cause of death. 2. To compare the adrenal changes in various layers along with sudden natural death. 3. To compare the adrenal changes in person dying due to debilitated condition like TB, CANCER. 4. To compare the adrenal changes in chronic hypertensive and end stage renal disease. 5. Death in corona pandemic due to COVID-19. 6. Death due to poisoning. Material and Methods- This observational cross section study will be carried out in the department of forensic medicine and toxicology on 100 cases in JLN Medical college and attached hospitals with cooperation from the department of pathology after obtaining due permission from the institutional ethical committee. Conclusion- Adrenal lesion can present in various forms at autopsy. Non-neoplastic Lesions should be given equal importance as neoplastic. An enlarged adrenal does not always indicate malignancy. There are many clinical conditions in which adrenals are affected as secondary phenomenon. Gross and histo-morphological examination of the tissue can diagnose the adrenal lesions with great accuracy and is beneficial for patient’s further survival, in setups where facilities to perform adrenal biopsies are available. Adrenals should be investigated as a part of routine autopsy procedure in all post-mortem cases.

Autopsy, adrenal gland, histo-morphological.

[1] Hedeland, H., Ostberg, G., Hokfelt, B. 1986. On the prevalence of adrenocortical adenomas in an autopsy material in relation to hypertension and diabetes. Acta Med Scand., 211,1968
[2] Khuri, F.J., Alton, D.J., Harde, B.E. et al. 1980. Adrenal hemorrhage in neonates: Report of 5 cases and review of the literature. Journal of urology, 124 : 684-699.
[3] Redman, B.G., Pazdur, R., Zinger, A.P., Loredo, R. 1987.Prospective evaluation of adrenal insufficiency in patients with adrenal metastasis. Cancer., 60 :103.
[4] Rich, A.R. 1944. A peculiar type of adrenal cortical damage associated with acute infections,and its possible relation to circulatory collapse. Bull John Hopkins Hosp., 74:1,1944.
[5] Russi, S., Blumenthal, H. T., Gray, S. H. 1945. Small adenomas of the adrenal cortex in hypertension and diabetes. Arch Intern Med., 76 : 284 ,1945.
[6] Salkade, H.P. Divate, S. Vaideeswar, P. et al. 2005. A study of autopsy findings in 62 cases of leptospirosis in a metropolitan city of India. Journal of postgraduate medicine; 51(3);169-173.
[7] Shamma, A.H., Goddard, J.W., Sommers, S.C. 1958. A study of the adrenal status in hypertension, J chronic Dis., 8: 587. Spain, D.M., Weinsaft, P. 1964. Solitary adrenal cortical adenoma in elderly female. Frequency.Arch Pathol., 78:.