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International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

Ophthalmic Ointment & Formulation: A Review

Nitish Kumar , Rajesh Kumar , Meenakshi Malhotra , Ajeet Pal Singh , Amar Pal Singh , Ritu Rani


International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-8,Issue-2, April - June 2024, Pages 47-60 , 10.22161/ijmpd.8.2.6

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Article Info: Received: 07 Mar 2024; Received in revised form:21 Apr 2024; Accepted:04 May 2024; Available online: 13 May 2024

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Using ointments as an eye drug delivery system gives topical therapy a significant new aspect. Ointments are a great way to increase ocular contact duration and are generally safe and well-tolerated. Increased contact time results in higher drug levels in the eyes. Experimental evidence, however, suggests that corticosteroid ointments do not enter the eye as deeply as suspension solutions do. This could be related to both the specific steroid component and the drug's binding to the ointment base. Ointments can get contaminated, just like other ophthalmic preparations. It is not recommended to apply ophthalmic ointments to eyes that have open sores. It seems safe and effective to apply ointments to postoperative eyes where wound closure is secure.

Contamination-entrapment of corneal, drug-base compatibility, duration of drug contact, emulsifiers, ophthalmic ointments, and ocular penetration.

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