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International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

Neoadjuvant Chemotherapy (NACT) In Advanced Epithelial Ovarian Cancer: A Review

Khushi , Rajesh Kumar , Ajeet pal singh , Amar pal singh , Meenakshi Malhotra


International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-8,Issue-2, April - June 2024, Pages 1-7 ,

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Article Info: Received: 05 Feb 2024; Received in revised form:17 Mar 2024; Accepted: 25 Mar 2024; Available online: 04 Apr 2024

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Ovarian cancer is considered to be the third most common cancer in Indian women and eight as global , 2018 facts sheet. It is a leading cause of death in Indian women due to cancer and fifth most common cause of death in women. The age that is affected by ovarian cancer is mostly above 50 years of women. Ovarian cancer is caused in ovaries and can also spread in the underlying organs if not diagnosed properly. Ovarian cancer can be divided further in two sub-types. Type1: Tumors mostly arise from the typical Borderline ( proliferative ) tumors. These are the early stage tumors [Stage I & II] Type2: Tumors are high-grade serious carcinomas, intraepithelial carcinoma and these are the advanced stage tumors having highly proliferative & rapid progression [Stage III & IV] This review mainly addresses the [Stage III & IV] diagnosis of Epithelial ovarian cancer by NACT (Neoadjuvant chemotherapy). The aim of this review is to evaluate the results and the possibilities of NACT procedure in curing Epithelial ovarian cancer.

EOC; cytoreduction; debulking surgeries; bevacizumab ;disparities in treatment; epithelial ovarian cancer; laparoscopy in oncology.

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