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NAAS Journal 2026

International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

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  3. Vol-8,Issue-2, April - June 2024
  4. Apoptosis

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Apoptosis

Ranjit Kumar , Rajesh Kumar , Ajeetpal Singh , Amarpal Singh , Prachi Sharma


International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-8,Issue-2, April - June 2024, Pages 24-27 ,

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Article Info: Received: 25 Feb 2024; Received in revised form:10 Apr 2024; Accepted: 20 Apr 2024; Available online: 02 May 2024

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The term "apoptosis" originates from the Greek language, where it signifies the process of "dropping off" or "falling off." In the context of nature, it specifically refers to the shedding of petals from flowers or leaves from trees, reflecting a natural and orderly process of cellular elimination. In biological terms, apoptosis involves a meticulously orchestrated sequence of molecular events within a cell, leading to its systematic self-destruction. This process is tightly regulated and serves various crucial functions in maintaining tissue homeostasis, development, and eliminating damaged or unnecessary cells from the body. During apoptosis, the cell undergoes distinct morphological changes, including condensation of the nucleus, fragmentation of DNA, and formation of apoptotic bodies. These changes facilitate the efficient removal of the dying cell without causing inflammation or damage to neighboring cells. Once the cell has undergone apoptosis, it is typically engulfed and digested by neighboring cells, a process known as phagocytosis. This ensures the prompt and efficient clearance of cellular debris, preventing any potential harmful effects on the surrounding tissue. Overall, apoptosis plays a vital role in shaping the development and maintenance of multicellular organisms by eliminating unwanted or compromised cells, thereby contributing to tissue remodeling, immune response regulation, and overall organismal health.

Apoptosis, Programmed cell death, Cellular self-destruction, Molecular events, Tissue homeostasis

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