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International Journal Of Medical, Pharmacy And Drug Research(IJMPD)

Acute transverse myelitis in puerperal women

Patrícia Leite Brito , Taiane Bentes Kimura , Henrique Bacellar


International Journal of Medical, Pharmacy and Drug Research(IJMPD), Vol-6,Issue-5, September - October 2022, Pages 12-15 , 10.22161/ijmpd.6.5.3

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Article Info: Received: 04 Sep 2022; Received in revised form: 19 Sep 2022; Accepted: 26 Sep 2022; Available online: 04 Oct 2022

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Transverse myelitis is a pathology, whose etiology is associated with autoimmune or infectious diseases, which directly affects the spinal cord, coursing with motor, sensory and acute or subacute dysfunction9. We report a case of a 32-year-old multiparous woman who, after the first postpartum day, reported pain and paresthesia in the lumbar and lower limbs with progressive worsening. Patient started clinical investigation, with orthopedic causes ruled out, together with the neurology and neurosurgery team. She underwent magnetic resonance imaging of the thoracic and lumbar spine where infectious neuropathy was evidenced at L4-L5. Patient was transferred to a referral hospital where Mycobacterium tuberculosis was evidenced as the cause and, when performing a rapid test for SARS-CoV-2, it was positive.

puerperium, acute myelitis, tuberculosis infection.

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[14] Scott TF, Frohman EM, De Seze J, Gronseth GS, Weinshenker BG. Evidence-based guideline: clinical evaluation and treatment of transverse myelitis. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2011;
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[18] Scott TF, Frohman EM, De Seze J, Gronseth GS, Weinshenker BG; Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Evidence-based guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2011 Dec 13;77(24):2128-34. doi: 10.1212/WNL.0b013e31823dc535. Epub 2011 Dec 7. PMID: 22156988.
[19] 1 Vol XX 2011 - Nascer e Crescer Magazine - Hospital.pdf. , [n.d.].
[20] CHENG, V.C.C. et al. Peripartum Tuberculosis as a Form of Immunorestitution Disease. Eur J Clin Microbiol Infect Dis, v. 22, p. 313–317, 2003.
[21] JONSSON, J. et al. Increased risk of active tuberculosis during pregnancy and postpartum: a register-based cohort study in Sweden. [n.d.].
[22] MARTÍNEZ, C. et al. Case Review Transversal Mielitis Clinical Analysis Abstract. [s.l: s.n.].
[23] ORTEGA-ROSALES, A.; DELGADO-TORRES, N.; BURNEO-ROSALES, C. A rare neurological complication of tuberculosis: Transverse myelitis. IDCases, v. 17, 1 Jan. 2019
[24] RODRÍGUEZ, Y. et al. Guillain–Barré syndrome, transverse myelitis and infectious diseasesCellular and Molecular Immunology, 2018. Available at: . Accessed on: 19 jun. 2020
[25] ROMAN, G.C.; KERR, D. Proposed diagnostic criteria and nosology of acute transverse myelitis [6] (multiple letters). Neurology, v. 60, no. 4, p. 730–731, 2003.
[26] West TW. Transverse myelitis--a review of the presentation, diagnosis, and initial management. Discov Med. 2013 Oct;16(88):167-77. PMID: 24099672.
[27] Martínez, Cecilia & Médica, Mena & Moreno Cortes, Eider & Álvaro, Muriel & Mauricio, Ocampo. (2018). Transverse Myelitis Clinical Analysis and Case Review. Risaralda Medical Journal. 24. 139-142. 10.22517/25395203.9386.
[28] Martins, Leticia & Fernandes, Mariana & Amanda, Raquel & Gotardo, Tassia & Geralda, Tatiliana & Kashiwabara, Kashiwabara. (2020). ACUTE TRANSVERSE MYELITIS: LITERATURE REVIEW ACUTE TRANSVERSE MYELITUS LITERATURE REVIEW. BJ Kines-National Journal of Basic & Applied Sciences. 30. 89-94
[29] Scott TF, Frohman EM, De Seze J, Gronseth GS, Weinshenker BG. Evidence-based guideline: clinical evaluation and treatment of transverse myelitis. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2011;
[30] PEREIRA, S.L.A; Prospective Study of Longitudinally Extensive Transverse Myelitis: analysis of clinical, laboratory and imaging factors. The original version