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International Journal Of Horticulture, Agriculture And Food Science(IJHAF)

LC-MS Profiling of methanolic extract of Pueraria tuberosa (Roxb. ex Willd.) DC. tubers

Bindu T.K. , P.S. Udayan

International Journal of Horticulture, Agriculture and Food science(IJHAF), Vol-2,Issue-5, September - October 2018, Pages 190-198, 10.22161/ijhaf.2.5.4

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LC-MS profiling has been developed for the characterization of chemical constituents present in the methanolic extract of Pueraria tuberosa tubers. As a result, 61 compounds were detected using m/z value. Swietenine, Vigabatrin, Barbituric acid, Rhoifolin, Cetrimonium bromide, Octanoic acid, Caprylic acid and 4Z-Decenedioic acid were some of the important phytoconstituents with interesting biological activities. Among the peaks in the chromatogram, 7 unknown compounds were also identified.

LC-MS profiling, methanolic extract, Pueraria tuberosa, chemical constituents.

[1] Angehagen M, Ben-Menachem E, Rönnbäck L and Hansson E. (2003). Novel Mechanisms of Action of Three Antiepileptic Drugs, Vigabatrin, Tiagabine, and Topiramate. Neurochemical Research. 28 (2): 333–340.
[2] Asharf A, Sarfraz R. A, Mahmood A, Din M. U. (2015). Chemical composition and in vitro antioxidant and antitumor activities of Eucalyptus camaldulensis Dehn. leaves. Industrial Crops and Products.74: 241–248.
[3] Chopra R. N, Nayar S. L and Chopra I. C. 1992. Glossary of Indian Medicinal Plant Council for Scientific and Industrial Research, Government of India, New Delhi, India.
[4] Dewanjee S, Maiti A, Das A. K, Mandal S. C and Dey S. P. (2009). Swietenine: a potential oral hypoglycemic from Swietenia macrophylla seed. Fitoterapia. 80 (4): 249-51.
[5] Gupta R. S, Sharma R, and Sharma A. (2004). “Antifertility effects of Pueraria tuberosa root extract in male rats,” Pharmaceutical Biology. 42 (8): 603–609.
[6] Hsu F.L , Liu I.M , Kuo D.H, Chen W.C , Su H.C and Cheng J.T. (2003). Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. Journal of Natural Products. 66 (6): 788-792.
[7] Ito E , Yip K. W, Katz D , Fonseca S. B , Hedley D .W, Chow S , Xu G. W , Wood T. E , Bastianutto C , Schimmer A. D , Kelley S. O and Liu F. F. (2009). Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer. Molecular Pharmacology. 76 (5): 969-983.
[8] Krug D, Zurek G, Revermann O, Vos M, Velicer G. J and Muller R. (2008). Discovery the hidden secondary metabollome of Myxoccus xanthus: A study of intraspecific diversity. Applied and Environmental Microbiology. 74 (10): 3058-68.
[9] Ma L, Li S, Zheng H, Chen J, Lin L, Ye X, Chen Z, Xu Q, Chen T, Yang J, Qiu N, Wang G, Peng A, Ding Y, Wei Y and Chen L. (2011). Synthesis and biological activity of novel barbituric and thiobarbituric acid derivatives against non-alcoholic fatty liver disease. European Journal of Medicinal Chemistry. 46 (6): doi: 10.1016/j.ejmech.2011.02.033.
[10] Nair M. K, Joy J, Vasudevan P, Hinckley L, Hoagland T. A and Venkitanarayanan K. S (2005). Antibacterial effect of caprylic acid and monocaprylin on major bacterial mastitis pathogens. Journal of Dairy Science. 88: 3488-3495.
[11] Refaat. J, Yehia S. Y , Ramadan M. A and Kamel M. S. (2015). Rhoifolin: a review of sources and biological activities. International Journal of Pharmacognosy. 2(3): 102-109.
[12] Santos F. S, Donoghue A. M, Venkitanarayanan K, Metcalf J. H, Reyes-Herrera I, Dirain M. L, Aguiar V. F, Blore P. J and Donoghue D. J. (2009). The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. Poultry science. 88: 61-64.
[13] Tahir H. U, Sarfraz A. R, Asharf A and Adil S. (2016). Chemical composition and anti-diabetic activity of essential oils obtained from two spices (Syzygium aromaticum and Cuminum cyminum). International Journal of Food Properties. 19: 2156–2164.
[14] Villas-Boas S.G , Mas S, Akesson M, Smedsgaard J and Nielson J. (2005). Mass spectrometry in metabolom analysis. Mass Spectrometry Reviews. 24: 613-646.
[15] Wang X, Sakuma T, Asafu-Adjaye E and Shiu G. K. (1999). Determination of ginsenosides in plant extracts from Panax ginseng and Panax quinquefolius L. by LC/MS/MS. Analytical Chemistry.71: 1579-1584