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International Journal Of Forest, Animal And Fisheries Research(IJFAF)

Cow’s Mastitis produced by Unicellular Algae of the Genus Prototheca, an Emerging Disease: Treatment Evaluations (Literature Review)

Sorin Răpuntean

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DOI: 10.22161/ijfaf.1.4.3

Journal : International Journal Of Forest, Animal And Fisheries Research(IJFAF)


Mastitis induced by Prototheca have become emerging diseases over the last 10-15 years, evolving endemically in some farms, and leading to important economic losses.The diseased cows eliminate the algae by milk, with the risk of transmission to humans, which is why protothecosis is part of the zoonosis group.Many antibiotics and antifungals have been tried in the treatment of mastitis, but without result, even though the sensitivity of isolated strains was detected in vitro.In the present study we present the antibiotics and antifungals used by various authors in the treatment of mastitis with Prototheca spp, as well as the results obtained.Among antibiotics, good and consistent efficacy was obtained with: gentamicin, neomycin, kanamycin, colistin. In antifungals, good results include: amphotericin B, miconazole, mycostatin, ketoconazole, econazole, itraconazole, batrafen and clotrimazole.It has been concluded that mastitis produced by Prototheca species (especially P. zopfii) are incurable, and the slaughter of sick animals is recommended.In order to avoid spreading within the herd, monitoring will be carried out by applying a screening program and avoiding contaminated sources from the environment.

Mastitis, protothecosis, therapy, emerging disease.

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[115] *** Prototheca mastitis. Mastitis pathogen. Factsheet#9. University of Minnesota College of Veterinary Medicine. https://www.vdl.umn.edu/sites/vdl.umn.edu/files/Prototheca-mastitis.pdf
[116] *** Mastitis 3 is now Mastitis 4. http://www.canwestdhi.com/pdf_files/Prototheca%20M4%20PCR%20factsheet%20for%20producers%20-%20Jan%202014.pdf.