[1] Upadhya R K, Shenoy L, Venkateswaran R. Effect of intravenous dexmedetomidine administered as bolus or as bolus-plus-infusion on subarachnoid anesthesia with hyperbaric bupivacaine. J Anaesthesiol Clin Pharmacol. 2018;34(3):46–50.
[2] Murray CJL, Ikuta KS, Sharara F, Swetschinski L, Robles Aguilar G, Gray A, et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399:629–55. https:// doi.org/10.1016/S0140-6736(21)02724-0.
[3] Shlaes DM. The economic conundrum for antibacterial drugs. Antimicrob Agents Chemother. 2019;64:e02057–19. https://doi. org/10.1128/AAC.02057-19
[4] McKenna M. The antibiotic paradox: why companies can’t afford to create life-saving drugs. Nature. 2020;584:338–41. https://doi.org/10.1038/d41586-020-02418-x.
[5] Outterson K. Estimating the appropriate size of global pull incentives for antibacterial medicines. Health Aff. 2021;40:1758–65. https://doi.org/10.1377/hlthaff.2021.00688.
[6] Madden J, Outterson K. Trends in the global antibiotics market. Nat Rev Drug Disco. 2023;22:174. https://doi.org/10.1038/ d41573-023-00029-5
[7] MacGowan GA, Shapiro EP, Azhari H, Siu CO, Hees PS, Hutchins GM, et al. Noninvasive measurement of shortening in the fiber and cross-fiber directions in the normal human left ventricle and in idiopathic dilated cardiomyopathy. Circulation. 1997;96(2):535–41.
[8] Tooke, C.L.; Hinchliffe, P.; Bragginton, E.C.; Colenso, C.K.; Hvievonen, V.H.A.; Takebayeshi, Y.; Spencer, J. β-Lactamases and β-Lactamase Inhibitors in the 21st Century. J. Mol. Biol. 2019, 431, 3472–3500. [Google Scholar] [CrossRef] [PubMed]
[9] Bush, K. Past and Present Perspectives on β-Lactamases. Antimicrob. Agents Chemother. 2018, 62, e01076-18. [Google Scholar] [CrossRef] [PubMed] [Green Version]
[10] Bush, K.; Bradford, P.A. β-Lactams and β-Lactamase Inhibitors: An Overview. Cold Spring Harb. Perspect. Med. 2016, 6, a025247. [Google Scholar] [CrossRef]
[11] Drawz, S. M., and Bonomo, R. A. (2010) Three decades of β-lactamase inhibitors, Clin. Microbiol. Rev., 23, 160-201, doi: 10.1128/CMR.00037-09.
[12] Olugbenga OO. Bacterial Resistance; A Perspective on Beta-Lactamase Enzymes. Ec Microbiol. 2020;16(3):1–12
[13] Lobritz MA, Andrews IW, Braff D, Porter CBM, Gutierrez A, Furuta Y, et al. Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality. Cell Chem Biol [Internet]. 2022;29(2):276-286.e4. Available from: https://doi.org/10.1016/j.chembiol.2021.12.010
[14] Turner J, Muraoka A, Bedenbaugh M, Childress B, Pernot L, Wiencek M, et al. The Chemical Relationship Among Beta-Lactam Antibiotics and Potential Impacts on Reactivity and Decomposition. Front Microbiol. 2022;13(March):1–18.
[15] Rossi S. (Ed.). Australian Medicines Handbook 2004, Adelaide: Australian Medicines Handbook. ISBN 0- 9578521-4-2
[16] Pew Charitable Trusts, Antibiotics Currently in Global Clinical Development, https://www.pewtrusts.org/en/research-and-analysis/data-visualizations/2014/antibiotics-currently-in-clinical-development.
[17] C. L. Tooke, P. Hinchliffe, E. C. Bragginton, C. K. Colenso, V. H. A. Hirvonen, Y. Takebayashi and J. Spencer, J. Mol. Biol., 2019, 431, 3472–3500 CrossRef CAS PubMed.
[18] A. Krajnc, P. A. Lang, T. D. Panduwawala, J. Brem and C. J. Schofield, Curr. Opin. Chem. Biol., 2019, 50, 101–110 CrossRef CAS.
[19] B. Liu, R. E. L. Trout, G.-H. Chu, D. McGarry, R. W. Jackson, J. C. Hamrick, D. M. Daigle, S. M. Cusick, C. Pozzi and F. De Luca, J. Med. Chem., 2019, 63, 2789–2801 CrossRef
[20] J. L. Mainardi, J. E. Hugonnet, F. Rusconi, M. Fourgeaud, L. Dubost, A. N. Moumi, V. Delfosse, C. Mayer, L. Gutmann, L. B. Rice and M. Arthur, J. Biol. Chem., 2007, 282, 30414–30422 CrossRef CAS PubMed.
[21] M. Paetzel, R. E. Dalbey and N. C. Strynadka, Pharmacol. Ther., 2000, 87, 27–49 CrossRef CAS.
[22] M. Paetzel, R. E. Dalbey and N. C. Strynadka, Nature, 1998, 396, 186–190 CrossRef CAS PubMed.
[23] A. Allsop, G. Brooks, P. D. Edwards, A. C. Kaura and R. Southgate, J. Antibiot., 1996, 49, 921–928 CrossRef CAS PubMed.
[24] T. R. Malla, A. Tumber, T. John, L. Brewitz, C. Strain-Damerell, C. D. Owen, P. Lukacik, H. T. H. Chan, P. Maheswaran, E. Salah, F. Duarte, H. Yang, Z. Rao, M. A. Walsh and C. J. Schofield, Chem. Commun., 2021, 57, 1430–1433 RSC.
[25] N. A. Caveney, S. D. Workman, R. Yan, C. E. Atkinson, Z. Yu and N. C. J. Strynadka, Nat. Commun., 2021, 12, 2775 CrossRef CAS PubMed.
[26] E. J. Culp, N. Waglechner, W. Wang, A. A. Fiebig-Comyn, Y.-P. Hsu, K. Koteva, D. Sychantha, B. K. Coombes, M. S. Van Nieuwenhze and Y. V. Brun, Nature, 2020, 578, 582–587 CrossRef CAS PubMed.
[27] A. J. Egan, J. Errington and W. Vollmer, Nat. Rev. Microbiol., 2020, 18, 446–460 CrossRef CAS PubMed