IJFAF | Comparative Study between Conventional Antibiotics and Medicinal Plant on Urinary Tract Organisms

Indexing and Abstracting

Comparative Study between Conventional Antibiotics and Medicinal Plant on Urinary Tract Organisms

Osuntokun Oludaretemitope , Olufakuyeoluwatosin

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Journal : International Journal Of Forest, Animal And Fisheries Research(IJFAF)

Abstract:

This study reports the bacteriological aetiology of Urinary Tract Infections (UTIs), the effect of antibiotics, antimicrobial potency of Alstoniaboonei leaf extract and also compare the activity of antibiotics and the leaves extract of Alstoniaboonei on the isolated organisms among pregnant women attending the Antenatal clinics at the Federal Medical Centre Owo, Ondo State, Nigeria for a period of two weeks. A total of 50 mid-stream urine samples were collected from pregnant women between the ages of 15-40years. The urine samples from patients were cultured on MacConkey agar. The isolates were identified based on colonial morphology and biochemical tests using API 20 NE kits. This results showed that 22 urine samples had significant bacterial growths while 28 had no significant growth. The highest isolate was Escherichia coli (50.0%). This was followed by Klebsiellapneumoniae (22.7%), Pseudomonas aeruginosa(9.1%), Enterobacteraerogens (9.1%), Citrobacterfreundii (4.5%) and Proteus mirabilis (4.5%). The most effective antibiotics in this study were Gentamycin, Ofloxacin, Nitrofuratoin and Ciprofloxacin whileCefixime, Ceftazidime, Cefuroxime, Erytromycin, Cloxacillin, Augmentin and Ceftriaxone were resistant. The leaves extract of Alstoniaboonei produced the highest zone of inhibition at (100%) concentration and the zone of inhibition were 24.0mm, 20.0mm, 18.0mm, 16.0mm, 14.5mm, and 12.0mm respectively for Escherichia coli, Proteus mirabilis, Klebsiellapneumoniae, Pseudomonas aeruginosa, Enterobacter spp. andCitrobacter spp. to antibiotics used. The high effect of Alstoniaboonei leave reported in this study should be of great concern, and good personal hygiene should be practiced to avoid Urinary tract infections.The purpose of this research work is to isolate and identify Gram negative organisms found in the Urinary Tract,determine the in-vitro antibiotics sensitivity patterns of the bacterial isolates,determine the in-vitroAlstoniaboonei leaves extract sensitivity patterns of the bacterial isolates organisms and to compare the activity of conventional antibiotics and Alstoniaboonei leaves extract of the bacterial isolates.

Keywords:

Alstoniaboonei,Urinary Tract Infections (UTIs), Conventional antibiotics.

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